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引用文献

近年来,世界各地的科学家和研究机构纷纷采用吉尔生化的多肽、抗体和其他定制服务,发表了一系列高水平的研究论文(Cell, Science及其系列, Nature及其系列, Molecular Cell, Immunity, Neuron, PNAS, Cell Metabolism, Cancer Research, Gene & Development, Blood, Biomaterials, J Neuroscience, JBC等),论文数量超过一千篇。另外,由于吉尔生化为欧美的生物技术公司提供了大量的OEM产品,而使用这些产品所发表的论文并未记在吉尔生化名下。以下是摘选的使用吉尔生化产品和服务后发表的部分论文(全部论文下载到Endnote): 


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  2. Abd-Elgaliel, W.R., Gallazzi, F., and Lever, S.Z. (2007). Total solid-phase synthesis of bombesin analogs with different functional groups at the C-terminus. Journal of Peptide Science 13, 487-492.
  3. Abdel-Wahab, Y.H.A., Power, G.J., Flatt, P.R., Woodhams, D.C., Rollins-Smith, L.A., and Conlon, J.M. (2008). A peptide of the phylloseptin family from the skin of the frog Hylomantis lemur (Phyllomedusinae) with potent in vitro and in vivo insulin-releasing activity. Peptides 29, 2136-2143.
  4. Abdelrahim, A.S., Simerska, P., and Toth, I. (2012a). Development and characterization of anionic liposaccharides for enhanced oral drug delivery. International Journal of Pharmaceutics 430, 120-128.
  5. Abdelrahim, A.S., Simerska, P., and Toth, I. (2012b). Liposaccharide-based nanoparticulate drug delivery system. Tetrahedron 68, 4967-4975.
  6. Abdelrahim, A.S., Ziora, Z.M., Bergeon, J.A., Moss, A.R., and Toth, I. (2009). Design and synthesis of a series of novel, cationic liposaccharide derivatives as potential penetration enhancers for oral drug delivery. Tetrahedron 65, 9436-9442.
  7. Abourbeh, G., Shir, A., Mishani, E., Ogris, M., Rödl, W., Wagner, E., and Levitzki, A. (2012). PolyIC GE11 polyplex inhibits EGFR-overexpressing tumors. IUBMB Life 64, 324-330.
  8. Afonso, G., Scotto, M., Renand, A., Arvastsson, J., Vassilieff, D., Cilio, C.M., and Mallone, R. (2010). Critical parameters in blood processing for T-cell assays: Validation on ELISpot and tetramer platforms. Journal of Immunological Methods 359, 28-36.
  9. Agnew, A., Calderwood, D., Chevallier, O.P., Greer, B., Grieve, D.J., and Green, B.D. (2011). Chronic treatment with a stable obestatin analog significantly alters plasma triglyceride levels but fails to influence food intake; fluid intake; body weight; or body composition in rats. Peptides 32, 755-762.
  10. Agnew, A.J., Robinson, E., McVicar, C.M., Harvey, A.P., Ali, I.H.A., Lindsay, J.E., McDonald, D.M., Green, B.D., and Grieve, D.J. (2012). The gastrointestinal peptide obestatin induces vascular relaxation via specific activation of endothelium-dependent NO signalling. British Journal of Pharmacology 166, 327-338.
  11. Agopian, A., Gros, E., Aldrian-Herrada, G., Bosquet, N., Clayette, P., and Divita, G. (2009). A New Generation of Peptide-based Inhibitors Targeting HIV-1 Reverse Transcriptase Conformational Flexibility. J Biol Chem 284, 254-264.
  12. Aina, O.H., Marik, J., Liu, R., Lau, D.H., and Lam, K.S. (2005). Identification of novel targeting peptides for human ovarian cancer cells using "one-bead one-compound" combinatorial libraries. Mol Cancer Ther 4, 806-813.
  13. Akhter Hossain, M., Bathgate, R.A.D., Kong, C.K., Shabanpoor, F., Zhang, S., Haugaard-Jönsson, L.M., Rosengren, K.J., Tregear, G.W., and Wade, J.D. (2008). Synthesis, Conformation, and Activity of Human Insulin-Like Peptide 5 (INSL5). ChemBioChem 9, 1816-1822.
  14. Al-Ghaferi, N., Kolodziejek, J., Nowotny, N., Coquet, L., Jouenne, T., Leprince, J., Vaudry, H., King, J.D., and Conlon, J.M. (2010). Antimicrobial peptides from the skin secretions of the South-East Asian frog Hylarana erythraea (Ranidae). Peptides 31, 548-554.
  15. Al-Jallad, H.F., Myneni, V.D., Piercy-Kotb, S.A., Chabot, N., Mulani, A., Keillor, J.W., and Kaartinen, M.T. (2011). Plasma Membrane Factor XIIIA Transglutaminase Activity Regulates Osteoblast Matrix Secretion and Deposition by Affecting Microtubule Dynamics. PLoS ONE 6, e15893.
  16. Alcala, S., Klee, M., Fernandez, J., Fleischer, A., and Pimentel-Muinos, F.X. (2008). A high-throughput screening for mammalian cell death effectors identifies the mitochondrial phosphate carrier as a regulator of cytochrome c release. Oncogene 27, 44-54.
  17. Almeida, B., Ohlmeier, S., Almeida, A.J., Madeo, F., Leao, C., Rodrigues, F., and Ludovico, P. (2009). Yeast protein expression profile during acetic acid-induced apoptosis indicates causal involvement of the TOR pathway. Proteomics 9, 720-732.
  18. Alvares, R., Tulumello, D.V., Macdonald, P.M., Deber, C.M., and Prosser, R.S. (2013). Effects of a polar amino acid substitution on helix formation and aggregate size along the detergent-induced peptide folding pathway. Biochimica et Biophysica Acta (BBA) - Biomembranes 1828, 373-381.
  19. An, L., Liu, L., Wang, S., and Bazan, G.C. (2009). An Optical Approach for Drug Screening Based on Light-Harvesting Conjugated Polyelectrolytes. Angewandte Chemie 121, 4436-4439.
  20. An, T., Ouyang, W., Pan, W., Guo, D., Li, J., Li, L., Chen, G., Yang, J., Wu, S., and Tien, P. (2012). Amino acid derivatives of the (−) enantiomer of gossypol are effective fusion inhibitors of human immunodeficiency virus type 1. Antiviral Research 94, 276-287.
  21. Anderson, W.G., Leprince, J., and Conlon, J.M. (2008). Purification, structural characterization, and myotropic activity of a peptide related to des-Arg9-bradykinin from an elasmobranch fish, the little skate, Leucoraja erinacea. Peptides 29, 1280-1286.
  22. Antignani, A., and Youle, R.J. (2006). How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane? Curr Opin Cell Biol 18, 685-689.
  23. Arabski, M., Konieczna, I., Solowiej, D., Rogon, A., Kolesinska, B., Kaminski, Z., and Kaca, W. (2010). Are anti-Helicobacter pylori urease antibodies involved in atherosclerotic diseases? Clinical Biochemistry 43, 115-123.
  24. Arbel, N., Ben-Hail, D., and Shoshan-Barmatz, V. (2012). Mediation of the Antiapoptotic Activity of Bcl-xL Protein upon Interaction with VDAC1 Protein. J Biol Chem 287, 23152-23161.
  25. Arbel, N., and Shoshan-Barmatz, V. (2010). Voltage-dependent Anion Channel 1-based Peptides Interact with Bcl-2 to Prevent Antiapoptotic Activity. J Biol Chem 285, 6053-6062.
  26. Arbor, S., Kao, J., Wu, Y., and Marshall, G.R. (2008). c[D-pro-Pro-D-pro-N-methyl-Ala] adopts a rigid conformation that serves as a scaffold to mimic reverse-turns. Peptide Science 90, 384-393.
  27. Armarego, W.L.F., and Chai, C.L.L. (2009). Common Physical Techniques Used in Purification. In Purification of Laboratory Chemicals (Sixth Edition) (Oxford, Butterworth-Heinemann), pp. 1-60.
  28. Arzoine, L., Zilberberg, N., Ben-Romano, R., and Shoshan-Barmatz, V. (2009). Voltage-dependent Anion Channel 1-based Peptides Interact with Hexokinase to Prevent Its Anti-apoptotic Activity. J Biol Chem 284, 3946-3955.
  29. Asoodeh, A., Haghparast, A., Kashef, R., and Chamani, J. (2012). Pro-Inflammatory Cytokine Responses of A549 Epithelial Cells to Antimicrobial Peptide Brevinin-2R. International Journal of Peptide Research and Therapeutics, 1-6.
  30. Atik, A., and Yalcin, T. (2011). A Systematic Study of Acidic Peptides for b-Type Sequence Scrambling. Journal of the American Society for Mass Spectrometry 22, 38-48.
  31. Atik, A.E., Gorgulu, G., and Yalcin, T. (2012). The role of lysine ?-amine group on the macrocyclization of b ions. International Journal of Mass Spectrometry 316–318, 84-90.
  32. Aw, K.L.D., Yao, S.Q., and Uttamchandani, M. (2010). Nanodroplet Microarrays for High-Throughput Enzyme Screening. In Small Molecule Microarrays, M. Uttamchandani, and S.Q. Yao, eds. (Humana Press), pp. 79-93.
  33. Béliveau, F., Désilets, A., and Leduc, R. (2009). Probing the substrate specificities of matriptase, matriptase-2, hepsin and DESC1 with internally quenched fluorescent peptides. FEBS Journal 276, 2213-2226.
  34. Backlund, J., Li, C., Jansson, E., Carlsen, S., Merky, P., Nandakumar, K.-S., Haag, S., Ytterberg, J., Zubarev, R.A., and Holmdahl, R. (2012). C57BL/6 mice need MHC class II Aq to develop collagen-induced arthritis dependent on autoreactive T cells. Ann Rheum Dis, annrheumdis-2012-202055.
  35. Baeriswyl, V., and Heinis, C. (2013). Phage selection of cyclic peptide antagonists with increased stability toward intestinal proteases. Protein Eng Des Sel 26, 81-89.
  36. Bagheri, M., Keller, S., and Dathe, M. (2011). Interaction of W-Substituted Analogs of Cyclo-RRRWFW with Bacterial Lipopolysaccharides: the Role of the Aromatic Cluster in Antimicrobial Activity. Antimicrob Agents Chemother 55, 788-797.
  37. Bai, L., Zhu, L., Min, S., Liu, L., Cai, Y., and Yao, J. (2008). Surface modification and properties of Bombyx mori silk fibroin films by antimicrobial peptide. Applied Surface Science 254, 2988-2995.
  38. Bai, X.-Y., Liu, X.-C., Yang, Q., Tang, X.-D., and He, G.-W. (2011a). The Interaction Between Human Urotensin II and Vasodilator Agents in Human Internal Mammary Artery With Possible Clinical Implications. Ann Thorac Surg 92, 610-616.
  39. Bai, Y., Ling, Y., Shi, W., Cai, L., Jia, Q., Jiang, S., and Liu, K. (2011b). Heteromeric Assembled Polypeptidic Artificial Hydrolases with a Six-Helical Bundle Scaffold. ChemBioChem 12, 2647-2658.
  40. Bai, Y., Xue, H., Wang, K., Cai, L., Qiu, J., Bi, S., Lai, L., Cheng, M., Liu, S., and Liu, K. (2012a). Covalent fusion inhibitors targeting HIV-1 gp41 deep pocket. Amino Acids, 1-13.
  41. Bai, Y., Zhang, Z., Deng, M., Chen, L., He, C., Zhuang, X., and Chen, X. (2012b). Thermo- and pH-responsive microgels for controlled release of insulin. Polymer International 61, 1151-1157.
  42. Bai, Y., Zhang, Z., Zhang, A., Chen, L., He, C., Zhuang, X., and Chen, X. (2012c). Novel thermo- and pH-responsive hydroxypropyl cellulose- and poly (l-glutamic acid)-based microgels for oral insulin controlled release. Carbohydrate Polymers 89, 1207-1214.
  43. Baines, C.P. (2009). The molecular composition of the mitochondrial permeability transition pore. J Mol Cell Cardiol 46, 850-857.
  44. Baines, C.P., Kaiser, R.A., Purcell, N.H., Blair, N.S., Osinska, H., Hambleton, M.A., Brunskill, E.W., Sayen, M.R., Gottlieb, R.A., Dorn, G.W., et al. (2005). Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature 434, 658-662.
  45. Baines, C.P., Kaiser, R.A., Sheiko, T., Craigen, W.J., and Molkentin, J.D. (2007). Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death. Nat Cell Biol 9, 550-555.
  46. Bano, N., Romano, J.D., Jayabalasingham, B., and Coppens, I. (2007). Cellular interactions of Plasmodium liver stage with its host mammalian cell. International Journal for Parasitology 37, 1329-1341.
  47. Barnard, A.L., Chidgey, A.P., Bernard, C.C., and Boyd, R.L. (2009). Androgen depletion increases the efficacy of bone marrow transplantation in ameliorating experimental autoimmune encephalomyelitis. Blood 113, 204-213.
  48. Barros, A., Graças Mota, L., Aguiar Ferreira, C., Corrêa, N., Góes, A., Oliveira, M., and Cardoso, V. (2012). 99mTc-labeled bombesin analog for breast cancer identification. Journal of Radioanalytical and Nuclear Chemistry, 1-8.
  49. Basavaraj, S., Benson, H.A.E., Cruickshank, C., Brown, D.H., and Chen, Y. (2011). Development of a liquid chromatography/mass spectrometry methodology to separate, detect, characterize and quantify PEG-resveratrol prodrugs and the conjugation reaction precursors and intermediates. Rapid Communications in Mass Spectrometry 25, 1543-1551.
  50. Basiri, M., Mousavi, S., Basiri, H., and Rasooli, I. (2010). An epitopic approach to designing and characterization of a multiple antigenic polypeptide against Botulinum neurotoxins A and E. World Journal of Microbiology and Biotechnology 26, 1659-1666.
  51. Bauke Albada, H., Rosati, F., Coquière, D., Roelfes, G., and Liskamp, R.M.J. (2011). Enantioselective CuII-Catalyzed Diels–Alder and Michael Addition Reactions in Water Using Bio-Inspired Triazacyclophane-Based Ligands. European Journal of Organic Chemistry 2011, 1714-1720.
  52. Bazar, E., and Jelinek, R. (2010). Divergent Heparin-Induced Fibrillation Pathways of a Prion Amyloidogenic Determinant. ChemBioChem 11, 1997-2002.
  53. Bazar, E., Sheynis, T., Dorosz, J., and Jelinek, R. (2011). Heparin Inhibits Membrane Interactions and Lipid-Induced Fibrillation of a Prion Amyloidogenic Determinant. ChemBioChem 12, 761-767.
  54. Beaufils, C., Alexopoulos, C., Petraki, M.P., Tselepis, A.D., Coudevylle, N., Sakarellos-Daitsiotis, M., Sakarellos, C., and Cung, M.T. (2007). Conformational study of new amphipathic α-helical peptide models of apoA-I as potential atheroprotective agents. Peptide Science 88, 362-372.
  55. Beckham, S.A., Boyd, S.E., Reynolds, S., Willis, C., Johnstone, M., Mika, A., Simerská, P., Wijeyewickrema, L.C., Smith, A.I., Kemp, D.J., et al. (2009a). Characterization of a Serine Protease Homologous to House Dust Mite Group 3 Allergens from the Scabies Mite Sarcoptes scabiei. Journal of Biological Chemistry 284, 34413-34422.
  56. Beckham, S.A., Boyd, S.E., Reynolds, S., Willis, C., Johnstone, M., Mika, A., Simerska, P., Wijeyewickrema, L.C., Smith, A.I., Kemp, D.J., et al. (2009b). Characterization of a Serine Protease Homologous to House Dust Mite Group 3 Allergens from the Scabies Mite Sarcoptes scabiei. J Biol Chem 284, 34413-34422.
  57. Behbahani, H., Pavlov, P.F., Wiehager, B., Nishimura, T., Winblad, B., and Ankarcrona, M. (2010). Association of Omi/HtrA2 with [gamma]-secretase in mitochondria. Neurochemistry International 57, 668-675.
  58. Bhunia, A., Mohanram, H., Domadia, P.N., Torres, J., and Bhattacharjya, S. (2009a). Designed {beta}-Boomerang Antiendotoxic and Antimicrobial Peptides: STRUCTURES AND ACTIVITIES IN LIPOPOLYSACCHARIDE. J Biol Chem 284, 21991-22004.
  59. Bhunia, A., Mohanram, H., Domadia, P.N., Torres, J., and Bhattacharjya, S. (2009b). Designed β-Boomerang Antiendotoxic and Antimicrobial Peptides: STRUCTURES AND ACTIVITIES IN LIPOPOLYSACCHARIDE. Journal of Biological Chemistry 284, 21991-22004.
  60. Bhunia, A., Saravanan, R., Mohanram, H., Mangoni, M.L., and Bhattacharjya, S. (2011). NMR Structures and Interactions of Temporin-1Tl and Temporin-1Tb with Lipopolysaccharide Micelles: MECHANISTIC INSIGHTS INTO OUTER MEMBRANE PERMEABILIZATION AND SYNERGISTIC ACTIVITY. J Biol Chem 286, 24394-24406.
  61. Bigot, L., Zatylny-Gaudin, C., Rodet, F., Bernay, B., Boudry, P., and Favrel, P. (2012). Characterization of GnRH-related peptides from the Pacific oyster Crassostrea gigas. Peptides 34, 303-310.
  62. Bilodeau, M.L., and Hamm, H.E. (2007). Regulation of Protease-Activated Receptor (PAR) 1 and PAR4 Signaling in Human Platelets by Compartmentalized Cyclic Nucleotide Actions. J Pharmacol Exp Ther 322, 778-788.
  63. Bing, T., Chang, T., Yang, X., Mei, H., Liu, X., and Shangguan, D. (2011). G-quadruplex DNA aptamers generated for systemin. Bioorganic & Medicinal Chemistry 19, 4211-4219.
  64. Bongiovanni, M.N., Scanlon, D.B., and Gras, S.L. (2011). Functional fibrils derived from the peptide TTR1-cycloRGDfK that target cell adhesion and spreading. Biomaterials 32, 6099-6110.
  65. Bonnet, J., Mayonove, P., and Morris, M.C. (2008). Differential phosphorylation of Cdc25C phosphatase in mitosis. Biochemical and Biophysical Research Communications 370, 483-488.
  66. Boulanger, D.S.M., Oliveira, R., Ayers, L., Prior, S.H., James, E., Williams, A.P., and Elliott, T. (2010). Absence of Tapasin Alters Immunodominance against a Lymphocytic Choriomeningitis Virus Polytope. J Immunol 184, 73-83.
  67. Boutard, N., Jamieson, A.G., Ong, H., and Lubell, W.D. (2010). Structure–Activity Analysis of the Growth Hormone Secretagogue GHRP-6 by α- and β-Amino γ-Lactam Positional Scanning. Chemical Biology & Drug Design 75, 40-50.
  68. Boutard, N., Turcotte, S., Beauregard, K., Quiniou, C., Chemtob, S., and Lubell, W.D. (2011). Examination of the active secondary structure of the peptide 101.10, an allosteric modulator of the interleukin-1 receptor, by positional scanning using β-amino γ-lactams. Journal of Peptide Science 17, 288-296.
  69. Bozso, Z., Penke, B., Simon, D., Laczkó, I., Juhász, G., Szegedi, V., Kasza, Á., Soós, K., Hetényi, A., Wéber, E., et al. (2010). Controlled in situ preparation of A[beta](1-42) oligomers from the isopeptide "iso-A[beta](1-42)", physicochemical and biological characterization. Peptides 31, 248-256.
  70. Braun, S., Humphreys, C., Fraser, E., Brancale, A., Bochtler, M., and Dale, T.C. (2011). Amyloid-Associated Nucleic Acid Hybridisation. PLoS ONE 6, e19125.
  71. Brust, D., Hamann, A., and Osiewacz, H.D. (2010). Deletion of PaAif2 and PaAmid2, two genes encoding mitochondrial AIF-like oxidoreductases of Podospora anserina, leads to increased stress tolerance and lifespan extension. Curr Genet 56, 225-235.
  72. Bugatti, A., Chiodelli, P., Rosenbluh, J., Loyter, A., and Rusnati, M. (2010). BSA conjugates bearing multiple copies of the basic domain of HIV-1 Tat: Prototype for the development of multitarget inhibitors of extracellular Tat. Antiviral Research 87, 30-39.
  73. Bunschoten, A., Ippel, J., Kruijtzer, J., Feitsma, L., de Haas, C., Liskamp, R., and Kemmink, J. (2010). A peptide mimic of the chemotaxis inhibitory protein of <i>Staphylococcus aureus</i>: towards the development of novel anti-inflammatory compounds. Amino Acids, 1-10.
  74. Bunschoten, A., Ippel, J., Kruijtzer, J., Feitsma, L., de Haas, C., Liskamp, R., and Kemmink, J. (2011). A peptide mimic of the chemotaxis inhibitory protein of <i>Staphylococcus aureus</i>: towards the development of novel anti-inflammatory compounds. Amino Acids 40, 731-740.
  75. Busam, R.D., Thorsell, A.-G., Flores, A., Hammarström, M., Persson, C., Öbrink, B., and Hallberg, B.M. (2011a). Structural Basis of Tumor Suppressor in Lung Cancer 1 (TSLC1) Binding to Differentially Expressed in Adenocarcinoma of the Lung (DAL-1/4.1B). Journal of Biological Chemistry 286, 4511-4516.
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  80. Cai, C., Wang, L., and Dong, C.-M. (2006). Synthesis, characterization, effect of architecture on crystallization, and spherulitic growth of poly(L-lactide)-b-poly(ethylene oxide) copolymers with different branch arms. Journal of Polymer Science Part A: Polymer Chemistry 44, 2034-2044.
  81. Cai, X., Wang, R., Filloux, A., Waksman, G., and Meng, G. (2011). Structural and Functional Characterization of Pseudomonas aeruginosa CupB Chaperones. PLoS ONE 6, e16583.
  82. Calabrese, A., Good, N., Wang, T., He, J., Bowie, J., and Pukala, T. (2012). A Negative Ion Mass Spectrometry Approach to Identify Cross-Linked Peptides Utilizing Characteristic Disulfide Fragmentations. Journal of the American Society for Mass Spectrometry 23, 1364-1375.
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  85. Cao, L., Li, Z., Zhang, R., Wu, Y., Li, W., and Cao, Z. (2012b). StCT2, a new antibacterial peptide characterized from the venom of the scorpion Scorpiops tibetanus. Peptides 36, 213-220.
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  87. Cao, Y., Wang, Z., Bu, X., Tang, S., Mei, Z., and Liu, P. (2009). A Synthetic Peptide Derived from A1 Module in CRD4 of Human TNF Receptor-1 Inhibits Binding and Proinflammatory Effect of Human TNF-α. Inflammation 32, 139-145.
  88. Caporale, A., Gesiot, L., Sturlese, M., Wittelsberger, A., Mammi, S., and Peggion, E. (2012). Design, conformational studies and analysis of structure–function relationships of PTH (1–11) analogues: the essential role of Val in position 2. Amino Acids 43, 207-218.
  89. Caporale, A., Schievano, E., and Peggion, E. (2010a). Peptide–peptoid hybrids based on (1–11)-parathyroid hormone analogs. Journal of Peptide Science 16, 480-485.
  90. Caporale, A., Sturlese, M., Schievano, E., Mammi, S., and Peggion, E. (2010b). Synthesis and structural studies of new analogues of PTH(1–11) containing C<sup>α</sup>-tetra-substituted amino acids in position 8. Amino Acids 39, 1369-1379.
  91. Caporale, A., Woznica, I., Schievano, E., Mammi, S., and Peggion, E. (2010c). Role of the guanidine group in the N-terminal fragment of PTH(1–11). Amino Acids 38, 1269-1275.
  92. Carmona-Gutierrez, D., Eisenberg, T., Buttner, S., Meisinger, C., Kroemer, G., and Madeo, F. (2010). Apoptosis in yeast: triggers, pathways, subroutines. Cell Death Differ 17, 763-773.
  93. Casey, J.L., Coley, A.M., Parisi, K., and Foley, M. (2009). Peptide mimics selected from immune sera using phage display technology can replace native antigens in the diagnosis of Epstein-Barr virus infection. Protein Eng Des Sel 22, 85-91.
  94. Cazakoff, B.N., and Howland, J.G. (2011). AMPA receptor endocytosis in rat perirhinal cortex underlies retrieval of object memory. Learn Mem 18, 688-692.
  95. Ceraudo, E., Hierso, R., Tan, Y.-V., Murail, S., Rouyer-Fessard, C., Nicole, P., Robert, J.-C., Jamin, N., Neumann, J.-M., Robberecht, P., et al. (2012). Spatial proximity between the VPAC1 receptor and the amino terminus of agonist and antagonist peptides reveals distinct sites of interaction. FASEB J 26, 2060-2071.
  96. Ceraudo, E., Murail, S., Tan, Y.-V., Lacapere, J.-J., Neumann, J.-M., Couvineau, A., and Laburthe, M. (2008a). The Vasoactive Intestinal Peptide (VIP) {alpha}-Helix Up to C Terminus Interacts with the N-Terminal Ectodomain of the Human VIP/Pituitary Adenylate Cyclase-Activating Peptide 1 Receptor: Photoaffinity, Molecular Modeling, and Dynamics. Mol Endocrinol 22, 147-155.
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  1179. Zhang, H., Kusunose, J., Kheirolomoom, A., Seo, J.W., Qi, J., Watson, K.D., Lindfors, H.A., Ruoslahti, E., Sutcliffe, J.L., and Ferrara, K.W. (2008d). Dynamic imaging of arginine-rich heart-targeted vehicles in a mouse model. Biomaterials 29, 1976-1988.
  1180. Zhang, J., Ye, F., Lan, L., Jiang, H., Luo, C., and Yang, C.-G. (2011c). Structural Switching of Staphylococcus aureus Clp Protease: A KEY TO UNDERSTANDING PROTEASE DYNAMICS. J Biol Chem 286, 37590-37601.
  1181. Zhang, J., Zhang, H., Wang, L., Guo, X., Wang, X., and Yao, H. (2010a). Isolation and identification of antioxidative peptides from rice endosperm protein enzymatic hydrolysate by consecutive chromatography and MALDI-TOF/TOF MS/MS. Food Chemistry 119, 226-234.
  1182. Zhang, J.V., Klein, C., Ren, P.-G., Kass, S., Donck, L.V., Moechars, D., and Hsueh, A.J.W. (2007a). Response to Comment on "Obestatin, a Peptide Encoded by the Ghrelin Gene, Opposes Ghrelin's Effects on Food Intake". Science 315, 766d-.
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  1184. Zhang, K., Ou, M., Wang, W., and Ling, J. (2009c). Effects of quorum sensing on cell viability in Streptococcus mutans biofilm formation. Biochemical and Biophysical Research Communications 379, 933-938.
  1185. Zhang, L.-Y., Wang, H., Liang, Z., Shan, Y.-C., Zhang, L.-H., and Zhang, Y.-K. (2010b). Preparation and Evaluation of Novel Iron Immobilized Metal Affinity Chromatography Monolithic Column. Chinese Journal of Analytical Chemistry 38, 659-662.
  1186. Zhang, L., Fu, J., Xia, Z., Wu, P., and Zhang, X. (2011d). Synthesis and characterization of a well-defined amphiphilic block copolymer and its paclitaxel prodrug from methoxy poly(ethylene glycol) and oligomer of glycolic acid. Journal of Applied Polymer Science 122, 758-766.
  1187. Zhang, L., Liang, Z., Yang, K., Xia, S., Wu, Q., Zhang, L., and Zhang, Y. (2012b). Mesoporous TiO2 aerogel for selective enrichment of phosphopeptides in rat liver mitochondria. Analytica Chimica Acta 729, 26-35.
  1188. Zhang, L., Ren, F., Li, J., Ma, X., and Wang, P. (2009d). A Modified Coupled Enzyme Method for O-linked GlcNAc Transferase Activity Assay. Biological Procedures Online 11, 170-183.
  1189. Zhang, L., Wang, H., Liang, Z., Yang, K., Zhang, L., and Zhang, Y. (2011e). Facile preparation of monolithic immobilized metal affinity chromatography capillary columns for selective enrichment of phosphopeptides. Journal of Separation Science, n/a-n/a.
  1190. Zhang, L., Xu, J., Sun, L., Ma, J., Yang, K., Liang, Z., Zhang, L., and Zhang, Y. (2011f). Zirconium oxide aerogel for effective enrichment of phosphopeptides with high binding capacity. Analytical and Bioanalytical Chemistry 399, 3399-3405.
  1191. Zhang, L., Xu, Y., Yao, H., Xie, L., Yao, J., Lu, H., and Yang, P. (2009e). Boronic Acid Functionalized Core–Satellite Composite Nanoparticles for Advanced Enrichment of Glycopeptides and Glycoproteins. Chemistry – A European Journal 15, 10158-10166.
  1192. Zhang, P., Reichardt, A., Liang, H., Aliyari, R., Cheng, D., Wang, Y., Xu, F., Cheng, G., and Liu, Y. (2012c). Single Amino Acid Substitutions Confer the Antiviral Activity of the TRAF3 Adaptor Protein onto TRAF5. Sci Signal 5, ra81-.
  1193. Zhang, Q., Wang, Y., Ji, Q., Gu, J., Liu, S., Feng, X., Sun, C., Li, Y., and Lei, L. (2012d). Selection of Antiviral Peptides Against Mink Enteritis Virus Using a Phage Display Peptide Library. Curr Microbiol, 1-6.
  1194. Zhang, Q., Zhou, H., and Yan, B. (2010c). Reducing Nanotube Cytotoxicity Using a Nano-Combinatorial Library Approach. In Carbon Nanotubes, K. Balasubramanian, and M. Burghard, eds. (Humana Press), pp. 95-107.
  1195. Zhang, S.-l., Du, Y.-h., Wang, J., Yang, L.-h., Yang, X.-l., Zheng, R.-h., Wu, Y., Wang, K., Zhang, M.-s., and Liu, H.-r. (2010d). Endothelial dysfunction induced by antibodies against angiotensin AT1 receptor in immunized rats. Acta Pharmacol Sin 31, 1381-1388.
  1196. Zhang, S., Han, L., Li, C.-g., Wang, J., Wang, W., Yuan, Z., and Gao, X. (2012e). Synthetic receptor and its association with CTD peptides. Tetrahedron 68, 2357-2362.
  1197. Zhang, S., Hughes, R.A., Bathgate, R.A.D., Shabanpoor, F., Hossain, M.A., Lin, F., van Lierop, B., Robinson, A.J., and Wade, J.D. (2010e). Role of the intra-A-chain disulfide bond of insulin-like peptide 3 in binding and activation of its receptor, RXFP2. Peptides 31, 1730-1736.
  1198. Zhang, S., Wang, J., Han, L., Li, C., Wang, W., and Yuan, Z. (2010f). Colorimetric detection of bis-phosphorylated peptides using zinc(ii) dipicolylamine-appended gold nanoparticles. Sensors and Actuators B: Chemical 147, 687-690.
  1199. Zhang, S., Zheng, R., Yang, L., Zhang, X., Zuo, L., Yang, X., Bai, K., Song, L., Tian, J., Yang, J., et al. (2012f). Angiotensin type 1 receptor autoantibody from preeclamptic patients induces human fetoplacental vasoconstriction. Journal of Cellular Physiology, n/a-n/a.
  1200. Zhang, S., Zhong, N., Xue, F., Kang, X., Ren, X., Chen, J., Jin, C., Lou, Z., and Xia, B. (2010g). Three-dimensional domain swapping as a mechanism to lock the active conformation in a super-active octamer of SARS-CoV main protease. Protein & Cell 1, 371-383.
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  1202. Zhang, W., Ding, N., and Li, Y. (2011g). Synthesis and biological evaluation of analogues of the marine cyclic depsipeptide obyanamide. Journal of Peptide Science 17, 533-539.
  1203. Zhang, W., Du, X., Zhao, G., Jin, H., Kang, Y., Xiao, C., Liu, M., and Wang, B. (2009f). Levamisole is a potential facilitator for the activation of Th1 responses of the subunit HBV vaccination. Vaccine 27, 4938-4946.
  1204. Zhang, W., Wang, J., Su, B., Li, R., Ding, Z., Kang, Y., and Wang, B. (2011h). Cimetidine augments Th1/Th2 dual polarized immune responses to recombinant HBV antigens. Vaccine 29, 4862-4868.
  1205. Zhang, X., Luo, K., Wang, G., Nie, Y., He, B., Wu, Y., and Gu, Z. (2012g). Synthesis and inhibition study on tripeptide inhibitor modified poly(L-lysine) dendrimers. J Biomater Appl 27, 17-26.
  1206. Zhang, X., Yang, J., Liu, S., Lin, X., and Xie, Z. (2011i). Branched polyethyleneimine-bonded tentacle-type polymer stationary phase for peptides and proteins separations by open-tubular capillary electrochromatography. Journal of Separation Science 34, 3383-3391.
  1207. Zhang, X., Yu, C., Zhao, J., Fu, L., Yi, S., Liu, S., Yu, T., and Chen, W. (2007b). Vaccination with a DNA vaccine based on human PSCA and HSP70 adjuvant enhances the antigen-specific CD8+ T-cell response and inhibits the PSCA+ tumors growth in mice. The Journal of Gene Medicine 9, 715-726.
  1208. Zhang, Y.-G., Yue, L., Wang, Y.-X., Tao, X.-M., and Song, H.-Y. (2006a). Design of a Novel Plasminogen Activator Based on the Structure of Hirudin. Acta Biochimica et Biophysica Sinica 38, 531-536.
  1209. Zhang, Y., Hu, W., Shen, J., Tong, X., Yang, Z., Shen, Z., Lan, W., Wu, H., and Cao, C. (2011j). Cysteine 397 plays important roles in the folding of the neuron-restricted silencer factor/RE1-silencing transcription factor. Biochemical and Biophysical Research Communications 414, 309-314.
  1210. Zhang, Y., Jiang, W., Fan, Y., Wen, J., Hao, W., and Qian, M. (2008e). Engineering enhancement of the immune response to HBV DNA vaccine in mice by the use of LIGHT gene adjuvant. Journal of Virological Methods 153, 142-148.
  1211. Zhang, Y., Lai, C., Duan, J., Guan, N., Ullah, K., and Deng, Y. (2012h). Simulated microgravity affects semicarbazide-sensitive amine oxidase expression in recombinant Escherichia coli by HPLC-ESI-QQQ analysis. Applied Microbiology and Biotechnology 94, 809-816.
  1212. Zhang, Y., Li, S., Liu, Y., Lu, D., Chen, H., Huang, X., Liu, X., Meng, Z., Lin, H., and Cheng, C.H.K. (2010i). Structural diversity of the gnih/gnih receptor system in teleost: Its involvement in early development and the negative control of LH release. Peptides 31, 1034-1043.
  1213. Zhang, Y., Li, S., Shan, M., Pan, X., Zhuang, K., He, L., Gould, K., and Tien, P. (2007c). Hepatitis B virus core antigen epitopes presented by HLA-A2 single-chain trimers induce functional epitope-specific CD8+ T-cell responses in HLA-A2•1/Kb transgenic mice. Immunology 121, 105-112.
  1214. Zhang, Y., Liu, J.-Y., Yang, F., Zhang, Y.-J., Yao, Q., Cui, T.-Y., Zhao, X., and Zhang, Z.-D. (2009g). A new strategy for assembling multifunctional nanocomposites with iron oxide and amino-terminated PAMAM dendrimers. Journal of Materials Science: Materials in Medicine 20, 2433-2440.
  1215. Zhang, Y., Su, P., Liang, P., Liu, T., Liu, X., Liu, X.-Y., Zhang, B., Han, T., Zhu, Y.-B., Yin, D.-M., et al. (2010j). The DREAM Protein Negatively Regulates the NMDA Receptor through Interaction with the NR1 Subunit. J Neurosci 30, 7575-7586.
  1216. Zhang, Y., Wang, S.-N., Ma, S., Guan, J.-J., Li, D., Zhang, X.-D., and Zhang, Z.-D. (2008f). Self-assembly multifunctional nanocomposites with Fe3O4 magnetic core and CdSe/ZnS quantum dots shell. Journal of Biomedical Materials Research Part A 85A, 840-846.
  1217. Zhang, Y., Wang, Y., Xiang, Y., and Lee, W. (2012i). Prohibitins are involved in protease-activated receptor 1-mediated platelet aggregation. Journal of Thrombosis and Haemostasis 10, 411-418.
  1218. Zhang, Y., Xiao, S., Wang, L., Wang, H., Zhu, Y., Li, Y., and Deng, Y. (2010k). Absolute quantification of semicarbazide-sensitive amine oxidase in human umbilical artery by single-reaction monitoring with electrospray tandem mass spectrometry. Analytical and Bioanalytical Chemistry 397, 709-715.
  1219. Zhang, Y., Xiong, Q., Hu, X., Sun, Y., Tan, X., Zhang, H., Lu, Y., and Liu, J. (2012j). A novel atherogenic epitope from Mycobacterium tuberculosis heat shock protein 65 enhances atherosclerosis in rabbit and LDL receptor-deficient mice. Heart Vessels 27, 411-418.
  1220. Zhang, Y., Yang, H., Xiao, B., Wu, M., Zhou, W., Li, J., Li, G., and Christadoss, P. (2009h). Dendritic cells transduced with lentiviral-mediated RelB-specific ShRNAs inhibit the development of experimental autoimmune myasthenia gravis. Molecular Immunology 46, 657-667.
  1221. Zhang, Y., Yang, W., Chen, L., Shi, Y., Li, G., and Zhou, N. (2011k). Development of a novel DnaE intein-based assay for quantitative analysis of G-protein-coupled receptor internalization. Analytical Biochemistry 417, 65-72.
  1222. Zhang, Y., Yu, G., Wang, Y., Xiang, Y., Gao, Q., Jiang, P., Zhang, J., Lee, W., and Zhang, Y. (2011l). Activation of protease-activated receptor (PAR) 1 by frog trefoil factor (TFF) 2 and PAR4 by human TFF2. Cellular and Molecular Life Sciences, 1-10.
  1223. Zhang, Y., Zhao, J., He, L., Zhao, D., and Zhang, S. (2006b). Manganese (III) salen complex anchored onto MCM-41 as catalyst for the aerobic epoxidation of olefins. Microporous and Mesoporous Materials 94, 159-165.
  1224. Zhang, Z., Chen, L., Deng, M., Bai, Y., Chen, X., and Jing, X. (2011m). Biodegradable thermo- and pH-responsive hydrogels for oral drug delivery. Journal of Polymer Science Part A: Polymer Chemistry 49, 2941-2951.
  1225. Zhang, Z., Chen, L., Zhao, C., Bai, Y., Deng, M., Shan, H., Zhuang, X., Chen, X., and Jing, X. (2011n). Thermo- and pH-responsive HPC-g-AA/AA hydrogels for controlled drug delivery applications. Polymer 52, 676-682.
  1226. Zhang, Z., Lai, Y., Yu, L., and Ding, J. (2010l). Effects of immobilizing sites of RGD peptides in amphiphilic block copolymers on efficacy of cell adhesion. Biomaterials 31, 7873-7882.
  1227. Zhang, Z., Zheng, Q., Wu, Y., and Hao, D. (2010m). Compatibility of neural stem cells with functionalized self-assembling peptide scaffold <i>in vitro</i>. Biotechnology and Bioprocess Engineering 15, 545-551.
  1228. Zhao, C., Xue, X., Li, G., Sun, C., Sun, C., Qu, X., and Li, W. (2012a). Synthesis and Biological Evaluation of Oral Prodrugs Based on the Structure of Gemcitabine. Chemical Biology & Drug Design, no-no.
  1229. Zhao, C., Zhuang, X., He, C., Chen, X., and Jing, X. (2008). Synthesis of Novel Thermo- and pH-Responsive Poly(L-lysine)-Based Copolymer and its Micellization in Water. Macromolecular Rapid Communications 29, 1810-1816.
  1230. Zhao, C., Zhuang, X., He, P., Xiao, C., He, C., Sun, J., Chen, X., and Jing, X. (2009a). Synthesis of biodegradable thermo- and pH-responsive hydrogels for controlled drug release. Polymer 50, 4308-4316.
  1231. Zhao, K., Liu, Q., Yu, R., Li, Z., Li, J., Zhu, H., Wu, X., Tan, F., Wang, J., and Tang, X. (2009b). Screening of specific diagnostic peptides of swine hepatitis E virus. Virology Journal 6, 186.
  1232. Zhao, P., Wang, H., Yu, M., Cao, S., Zhang, F., Chang, J., and Niu, R. (2010a). Paclitaxel-Loaded, Folic-Acid-Targeted and TAT-Peptide-Conjugated Polymeric Liposomes: <i>In Vitro</i> and <i>In Vivo</i> Evaluation. Pharmaceutical Research 27, 1914-1926.
  1233. Zhao, R., Yu, X., Yu, H., Han, W., Zhai, L., Han, J., and Liu, J. (2009c). Immunoregulatory peptides from salivary glands of the horsefly, Tabanus pleskei. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 154, 1-5.
  1234. Zhao, X.L., Li, G.Z., Sun, B., Zhang, Z.L., Yin, Y.H., Tian, Y.S., Li, H., Li, H.L., Wang, D.S., and Zhong, D. (2010b). MMP-mediated cleavage of [beta]-dystroglycan in myelin sheath is involved in autoimmune neuritis. Biochemical and Biophysical Research Communications 392, 551-556.
  1235. Zhao, Y., Gao, S., Zhao, S., Li, Y., Cheng, L., Li, J., and Yin, Y. (2012b). Synthesis and characterization of disulfide-crosslinked alginate hydrogel scaffolds. Materials Science and Engineering: C 32, 2153-2162.
  1236. Zhao, Z., Hong, W., Zeng, Z., Wu, Y., Hu, K., Tian, X., Li, W., and Cao, Z. (2012c). Mucroporin-M1 Inhibits Hepatitis B Virus Replication by Activating the Mitogen-activated Protein Kinase (MAPK) Pathway and Down-regulating HNF4{alpha} in Vitro and in Vivo. J Biol Chem 287, 30181-30190.
  1237. Zhao, Z., Hong, W., Zeng, Z., Wu, Y., Hu, K., Tian, X., Li, W., and Cao, Z. (2012d). Mucroporin-M1 Inhibits Hepatitis B Virus Replication by Activating the Mitogen-activated Protein Kinase (MAPK) Pathway and Down-regulating HNF4α in Vitro and in Vivo. Journal of Biological Chemistry 287, 30181-30190.
  1238. Zhao, Z., Ma, Y., Dai, C., Zhao, R., Li, S., Wu, Y., Cao, Z., and Li, W. (2009d). Imcroporin, a New Cationic Antimicrobial Peptide from the Venom of the Scorpion Isometrus maculates. Antimicrob Agents Chemother 53, 3472-3477.
  1239. Zheng, J.-S., Chang, H.-N., Shi, J., and Liu, L. (2012a). Chemical synthesis of a cyclotide via intramolecular cyclization of peptide O-esters. SCIENCE CHINA Chemistry 55, 64-69.
  1240. Zheng, J., Wu, H.-T., Zhu, B.-W., Dong, X.-P., Zhang, M.-M., and Li, Y.-L. (2012b). Identification of antioxidative oligopeptides derived from autolysis hydrolysates of sea cucumber (Stichopus japonicus) guts. Eur Food Res Technol 234, 895-904.
  1241. Zheng, L.-N., Lin, H., Pawar, R., Li, Z.-X., and Li, M.-H. (2011). Mapping IgE binding epitopes of major shrimp (Penaeus monodon) allergen with immunoinformatics tools. Food and Chemical Toxicology 49, 2954-2960.
  1242. Zheng, Q., Gong, T., Sun, X., and Zhang, Z.-R. (2006a). Synthesis, characterization and <i>in vitro</i> evaluation of triptolide-lysozyme conjugate for renal targeting delivery of triptolide. Archives of Pharmacal Research 29, 1164-1170.
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